Urate excretion and urine flow in a lithium-induced diabetes insipidus rat model


The relationship of urine flow to the excretion and clearance of uric acid was studied in rats at their normal endogenous plasma urate concentrations during saline infusion, utilizing a lithium-induced diabetes insipidus model. Thirteen rats were pretreated with intraperitoneal lithium for 4–7 days, while six control animals received intraperitoneal sodium… (More)
DOI: 10.1007/BF00595707


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