Uraemic pruritus: relief of itching by gabapentin and pregabalin.

@article{Rayner2012UraemicPR,
  title={Uraemic pruritus: relief of itching by gabapentin and pregabalin.},
  author={Hugh C. Rayner and Jyoti Baharani and Stephen M. Smith and Vijayan Suresh and Indranil Dasgupta},
  journal={Nephron. Clinical practice},
  year={2012},
  volume={122 3-4},
  pages={
          75-9
        }
}
BACKGROUND Pruritus (skin irritation or itching) is common in patients with chronic kidney disease (CKD) stages 4 and 5. It is associated with disrupted sleep, reduced quality of life, depression and increased mortality. A video of a patient describing the symptoms is at vimeo.com/49458473. METHODS We used gabapentin or pregabalin in 71 consecutive patients, 82% male. 25 had CKD stage 4 or 5, median eGFR = 17, range 9-30; 40 were on haemodialysis; 6 on peritoneal dialysis. Median itch… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

Gabapentin for uremic pruritus in hemodialysis patients: a qualitative systematic review

  • Canadian journal of kidney health and disease
  • 2016
VIEW 9 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2017
VIEW 4 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Pruritus and Patient Reported Outcomes in Non-Dialysis CKD.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2019

Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges

  • International journal of nephrology and renovascular disease
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 13 REFERENCES

A comparative analysis of cetirizine, gabapentin and their combination in the relief of postburn pruritus

RB Ahuja, R Gupta, G Gupta, P Shrivastava
  • Burns
  • 2011

A longitudinal study of uremic pruritus in hemodialysis patients.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2010

The use of pregabalin in the treatment of uraemic pruritus in haemodialysis patients

G Aperis, C Paliouras, A Zervos, A Arvanitis, P Alivanis
  • J Ren Care
  • 2010

Uraemic pruritus. Clinical characteristics, pathophysiology and treatment

L Manenti, P Tansinda, A Vaglio
  • Drugs
  • 2009

Gabapentin: a promising drug for the treatment of uremic pruritus.

  • Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  • 2007

Similar Papers

Loading similar papers…