Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

@article{Grant2014UptakeOP,
  title={Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.},
  author={Robert M. Grant and Peter L. Anderson and Vanessa M. McMahan and Albert Y Liu and K Rivet Amico and Megha L. Mehrotra and Sybil G Hosek and Carlos Mosquera and Mart{\'i}n Casap{\'i}a and O. L. Quintero Montoya and Susan P Buchbinder and Valdilea Gonçalves Veloso and Kenneth H Mayer and Suwat Chariyalertsak and Linda-Gail Bekker and Esper G Kallas and Mauro Schechter and Juan V Guanira and Lane R. Bushman and David W. Burns and James F. Rooney and David V. Glidden},
  journal={The Lancet. Infectious diseases},
  year={2014},
  volume={14 9},
  pages={
          820-9
        }
}
BACKGROUND The effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake, adherence, and sexual practices. We aimed to assess these factors in a cohort of HIV-negative people at risk of infection. METHODS In our cohort study, men and transgender women who have sex with men previously enrolled in PrEP trials (ATN 082, iPrEx, and US Safety Study) were enrolled in a 72 week open-label extension. We measured drug concentrations in plasma and dried blood spots in seroconverters and a random… CONTINUE READING