Uptake of lectins by pulmonary alveolar type II cells: subsequent deposition into lamellar bodies.

@article{Williams1984UptakeOL,
  title={Uptake of lectins by pulmonary alveolar type II cells: subsequent deposition into lamellar bodies.},
  author={Mark Campbell Williams},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 20},
  pages={
          6383-7
        }
}
Type II cells of the alveolar epithelium of adult rats have been shown to internalize the ferritin-labeled lectin from Maclura pomifera (MPA-F). This alpha-galactose-binding molecule binds specifically to the apical plasma membrane of the cells. Once within the cell the lectin is cycled from pinocytic vesicles, to multivesicular bodies of two types, and finally to lamellar bodies, the storage granules of surfactant. Those multivesicular bodies that first contain MPA-F lack detectable lysosomal… CONTINUE READING

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