Uptake of indolmycin in gram-positive bacteria.

  title={Uptake of indolmycin in gram-positive bacteria.},
  author={Rolf G{\"u}nter Werner},
  journal={Antimicrobial agents and chemotherapy},
  volume={18 6},
The antimicrobial activity of indolmycin correlates with the generation time of the investigated strains. Thus, in Staphylococcus aureus ATCC 13150 with a 37-min generation time, the minimal inhibitory concentration (MIC) was 0.6 microgram ml-1, and in Bacillus subtilis ATCC 27142 with a generation time of 23 min, the MIC reached 10.5 micrograms ml-1. Competition experiments in staphylococci and B. subtilis with aromatic amino acids demonstrated that indolmycin uses the uptake systems that are… CONTINUE READING