Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants.

@article{SantosOcaa2002UptakeOE,
  title={Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants.},
  author={Carlos Santos-Oca{\~n}a and Thai Q Do and Sergio E. Padilla and Placido Navas and Catherine F. Clarke},
  journal={The Journal of biological chemistry},
  year={2002},
  volume={277 13},
  pages={
          10973-81
        }
}
Coenzyme Q (Q) is an essential component of the mitochondrial respiratory chain in eukaryotic cells but also is present in other cellular membranes where it acts as an antioxidant. Because Q synthesis machinery in Saccharomyces cerevisiae is located in the mitochondria, the intracellular distribution of Q indicates the existence of intracellular Q transport. In this study, the uptake of exogenous Q(6) by yeast and its transport from the plasma membrane to mitochondria was assessed in both wild… CONTINUE READING

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