Uptake of calcium by mitochondria: transport and possible function.

  title={Uptake of calcium by mitochondria: transport and possible function.},
  author={Thomas E. Gunter and Karlene K Gunter},
  journal={IUBMB life},
  volume={52 3-5},
Vertebrate mitochondria contain a complex system for transport of Ca2+ and related ions, consisting of two saturable modes of Ca2+ influx and two separate, saturable mechanisms of Ca2+ efflux. The characteristics of the mechanisms of Ca2+ uptake, the uniporter and the RaM, are discussed here and suggestions are made about how the mechanisms may work together and separately to mediate the two physiological roles with which they are most commonly associated-control of the rate of cellular ATP… CONTINUE READING

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