Uptake and turnover of L-(13N)-glutamate in the normal human heart and in patients with coronary artery disease

L-(13N)-glutamate (4–8 mCi) was administered IV to 27 patients with coronary artery disease and to 12 control subjects. Quantitative whole body imaging of the 13N label was performed in 31 individuals at different time intervals following the injection. Initial uptake of the total myocardium was estimated to be 5.0±0.88% of the dose. Standardized areas of… CONTINUE READING