Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells.

Abstract

The blood-brain barrier (BBB) formed by brain capillary endothelial cells (BCECs) constitutes a firm physical, chemical, and immunological barrier, making the brain accessible to only a few percent of potential drugs intended for treatment inside the central nervous system. With the purpose of overcoming the restraints of the BBB by allowing the transport… (More)
DOI: 10.1021/cn400093z

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