Uptake and degradation of blood-borne insulin by the olfactory bulb.

  title={Uptake and degradation of blood-borne insulin by the olfactory bulb.},
  author={W. A. Banks and Abba J. Kastin and Weihong Pan},
  volume={20 3},
Insulin found within the brain is derived from the blood and can affect various central nervous system (CNS) functions. The olfactory bulb contains one of the highest concentrations of insulin and insulin receptors within the CNS. To determine the mechanism underlying this high concentration of insulin, we used radioactively iodinated insulin to compare the blood to tissue transport rates and tissue degradation rates for the olfactory bulb, whole brain and spinal cord. We found that the… CONTINUE READING

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