Uptake and binding of serotonin by primary cultures of mouse astrocytes.

@article{Tardy1982UptakeAB,
  title={Uptake and binding of serotonin by primary cultures of mouse astrocytes.},
  author={Marcienne Tardy and Maria Fernanda Souza Costa and C. Fages and Josiane Bardakdjian and Pierre Gonnard},
  journal={Developmental neuroscience},
  year={1982},
  volume={5 1},
  pages={
          19-26
        }
}
Primary cultures of glia contain a high glial fibrillary acidic protein level and exhibit important glutamine synthetase activity. They take up serotonin via a high affinity carrier-mediated system with a Km of micromolar range. The Km of this transport process does not vary during cell growth or maturation; however, during the last period of morphological change induced by dibutyryl cyclic AMP, an increase in Vmax is observed. Chlorimipramine, fluoxetine and fenfluramine at 10-4 M inhibit this… CONTINUE READING

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Primary astroglial cultures

  • Neurochemical Research
  • 1986
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CITES BACKGROUND

Further characterization of [3H]fulunitrazepam binding sites on cultured mouse astroglia

Marcienne Tardy, C. Fages, +3 authors B. Rolland
  • Neurochemical Research
  • 1985
VIEW 2 EXCERPTS
CITES METHODS & BACKGROUND