Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1.

@article{Moore2003UpstreamSF,
  title={Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1.},
  author={Meredith Lee Moore and Edwards Amasa Park and Jeanie B. Mcmillin},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 19},
  pages={
          17263-8
        }
}
Transcriptional regulation of carnitine palmitoyltransferase-1beta (CPT-1beta) is coordinated with contractile gene expression through cardiac-enriched transcription factors, GATA4 and SRF. Metabolic modulation of CPT-1beta promoter activity has been described with the stimulation of gene expression by oleate that is mediated through the peroxisome proliferator-activated receptor (PPAR) pathway. The coactivator, peroxisomal proliferator-activated receptor gamma coactivator (PGC-1), enhances… CONTINUE READING
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