• DOI:10.1016/J.EJPHAR.2006.03.054
Corpus ID: 25052339

Upstream signaling of protein kinase C-epsilon in xenon-induced pharmacological preconditioning. Implication of mitochondrial adenosine triphosphate dependent potassium channels and phosphatidylinositol-dependent kinase-1.

@article{Weber2006UpstreamSO,
  title={Upstream signaling of protein kinase C-epsilon in xenon-induced pharmacological preconditioning. Implication of mitochondrial adenosine triphosphate dependent potassium channels and phosphatidylinositol-dependent kinase-1.},
  author={N. Weber and O. Toma and H. Damla and J. I. Wolter and W. Schlack and B. Preckel},
  journal={European journal of pharmacology},
  year={2006},
  volume={539 1-2},
  pages={
          1-9
        }
}

N. Weber, O. Toma, +3 authors B. Preckel

Published 2006

Chemistry, Medicine

European journal of pharmacology

Xenon elicits preconditioning of the myocardium via protein kinase C-epsilon. We determined the implication of (1) the mitochondrial adenosinetriphosphate dependent potassium (K(ATP)) channels and (2) the 3'phosphatidylinositol-dependent kinase-1 (PDK-1) in activating protein kinase C-epsilon. For infarct size measurements, anaesthetized rats were subjected to 25 min of coronary artery occlusion followed by 120 min of reperfusion. Rats received xenon 70% during three 5-min periods before… CONTINUE READING

View on PubMed

doi.org

Save to Library

Create Alert

Cite

Launch Research Feed