Upregulation of tyrosine kinase TKT by the Epstein-Barr virus transactivator Zta.

@article{Lu2000UpregulationOT,
  title={Upregulation of tyrosine kinase TKT by the Epstein-Barr virus transactivator Zta.},
  author={J J Lu and Szu Yu Jenny Chen and Hui Hoon Chua and You Shi Liu and Yung T. Huang and Yao Fu Chang and James Yok-Jen Chen and T S Sheen and Ching Hui Tsai},
  journal={Journal of virology},
  year={2000},
  volume={74 16},
  pages={7391-9}
}
The Zta protein is a key transactivator involved in initiating the Epstein-Barr virus (EBV) lytic cascade. In addition to transactivating many viral genes, Zta has the capacity to influence host cellular signals by binding to promoter regions or by interacting with several important cellular factors. Based on the observation that tyrosine kinases play central roles in determining the fate of cells, a kinase display assay was used to investigate whether cells expressing Zta have an altered… CONTINUE READING
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…