Upregulation of the long noncoding RNA HOTAIR predicts recurrence in stage Ta/T1 bladder cancer

  title={Upregulation of the long noncoding RNA HOTAIR predicts recurrence in stage Ta/T1 bladder cancer},
  author={Ting-hua Yan and Sui-wan Lu and Yong-qing Huang and Gan-bo Que and Jun-Hui Chen and Yongping Chen and Hong-bin Zhang and Xing-Lan Liang and Jin-hua Jiang},
  journal={Tumor Biology},
Stage Ta/T1 urothelial carcinoma of the bladder (Ta/T1 BC) has a marked tendency to recurrence. Long noncoding RNA HOTAIR has been reported to be expressed in some human cancers such as breast cancer, and it may be positively correlated with patient’s prognosis. The aim of our study was to evaluate the prognostic value of HOTAIR in Ta/T1 BC. HOTAIR expression in Ta/T1 BC tissues and adjacent normal tissues was collected from 110 patients and measured by real-time quantitative PCR. The… CONTINUE READING
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Long non-coding RNAHOTAIR reprograms chromatin state to promote cancer

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