Upregulation of parathyroid VDR expression by extracellular calcium is mediated by ERK1/2-MAPK signaling pathway.

  title={Upregulation of parathyroid VDR expression by extracellular calcium is mediated by ERK1/2-MAPK signaling pathway.},
  author={S. Ca{\~n}adillas and Roc{\'i}o Canalejo and M. Rodriguez-Ortiz and J. Martinez-Moreno and J. C. Estepa and R. Zafra and Jos{\'e} P{\'e}rez and J. Mu{\~n}oz-Casta{\~n}eda and A. Canalejo and M. Rodr{\'i}guez and Y. Almad{\'e}n},
  journal={American journal of physiology. Renal physiology},
  volume={298 5},
  • S. Cañadillas, Rocío Canalejo, +8 authors Y. Almadén
  • Published 2010
  • Medicine, Chemistry
  • American journal of physiology. Renal physiology
  • We have previously demonstrated that the activation of rat parathyroid calcium-sensing receptor (CaSR) upregulates VDR expression in vivo (Garfia B, Cañadillas S, Luque F, Siendones E, Quesada M, Almadén Y, Aguilera-Tejero E, Rodríguez M. J Am Soc Nephrol 13: 2945-2952, 2002; Rodriguez ME, Almaden Y, Cañadillas S, Canalejo A, Siendones E, Lopez I, Aguilera-Tejero E, Martin D, Rodriguez M. Am J Physiol Renal Physiol 292: F1390-F1395, 2007). The present study was designed to characterize the… CONTINUE READING
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