Upregulation of microRNA-23a regulates proliferation and apoptosis by targeting APAF-1 in laryngeal carcinoma.

@article{Zhang2015UpregulationOM,
  title={Upregulation of microRNA-23a regulates proliferation and apoptosis by targeting APAF-1 in laryngeal carcinoma.},
  author={Xiaowen Zhang and Ning Liu and Sheng Chen and Yueping Wang and Kai-lai Sun and Zhen-ming Xu and Wei-Neng Fu},
  journal={Oncology letters},
  year={2015},
  volume={10 1},
  pages={410-416}
}
MicroRNA-23a (miR-23a) is a potential biomarker for laryngeal cancer. Apoptotic protease activating factor 1 (APAF-1) was recently demonstrated to be a target of miR-23a. However, whether miR-23a exerts its effects via APAF-1 in laryngeal cancer, remains unknown. In the present study, miR-23a expression was detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). APAF-1 mRNA and protein expression levels were assayed by RT-qPCR and western blotting, respectively… CONTINUE READING
6 Extracted Citations
0 Extracted References
Similar Papers