Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma

  title={Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma},
  author={Bin-kui Li and P. Huang and Ji-Liang Qiu and Y J Liao and Jian Hong and Yun-fei Yuan},
  booktitle={Diagnostic pathology},
BACKGROUND MicroRNA-106b (miR-106b) is a member of the miR-106b ~ 25 cluster. It has been reported that miR-106b acts as an oncogene and is upregulated in many human cancers. However, the prognostic value of miR-106b in hepatocellular carcinoma (HCC) remains unclear. The aim of this study was to investigate the clinical significance of miR-106b expression in HCC. METHODS We determined the expression level of miR-106b in 104 cases of paired HCC and adjacent non-tumor tissues by quantitative… CONTINUE READING
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