Upregulation of macrophage migration inhibitory factor and calgizzarin by androgen in TM4 mouse Sertoli cells.

@article{Kasumi2006UpregulationOM,
  title={Upregulation of macrophage migration inhibitory factor and calgizzarin by androgen in TM4 mouse Sertoli cells.},
  author={Hiroyuki Kasumi and Shinji Komori and Kazuko Sakata and Naoko Yamamoto and Tomohiko Yamasaki and Yonehiro Kanemura and Koji Koyama},
  journal={Asian journal of andrology},
  year={2006},
  volume={8 5},
  pages={549-54}
}
AIM To identify proteins induced by androgen in Sertoli cells during spermatogenesis. METHODS We analyzed protein profiles in TM4 Sertoli cells treated with dihydrotestosterone (DHT) using surface enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF-MS). RESULTS We found increases in the expression of a 5.0-kDa protein at 15 min, an 11.3-kDa protein at 24 h and 4.3 kDa, 5.7 kDa, 5.8 kDa, 9.95 kDa and 9.98 kDa proteins at 48 h after the treatment. In contrast, the… CONTINUE READING

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