Upregulation of long noncoding RNA HOTTIP promotes metastasis of esophageal squamous cell carcinoma via induction of EMT

@inproceedings{Chen2016UpregulationOL,
  title={Upregulation of long noncoding RNA HOTTIP promotes metastasis of esophageal squamous cell carcinoma via induction of EMT},
  author={Xuemei Chen and Hong-yu Han and Yuqi Li and Qiuxiang Zhang and Kailan Mo and Size Chen},
  booktitle={Oncotarget},
  year={2016}
}
Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and deadly cancers worldwide, especially in Eastern Asia. The prognosis of ESCC remains poor; thus, it is still necessary to further dissect the underlying mechanisms and explore therapeutic targets of ESCC. Recent studies show that lncRNAs involve in the initiation and progression of various cancers including ESCC. HOTTIP has been recently revealed as oncogenic regulator in different cancers, however, whether HOTTIP is involved… CONTINUE READING
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Long non-coding RNAs in esophageal cancer: molecular mechanisms, functions, and potential applications

Journal of hematology & oncology • 2018
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