Upregulation of extrinsic apoptotic pathway in curcumin-mediated antiproliferative effect on human pancreatic carcinogenesis.

@article{Youns2013UpregulationOE,
  title={Upregulation of extrinsic apoptotic pathway in curcumin-mediated antiproliferative effect on human pancreatic carcinogenesis.},
  author={Mahmoud A. Youns and Gihan Mahmoud Fathy},
  journal={Journal of cellular biochemistry},
  year={2013},
  volume={114 12},
  pages={2654-65}
}
Pancreatic cancer is one of the most lethal human cancers, with almost identical incidence and mortality rates. Curcumin, derived from the rhizome of Curcuma longa, has a long history of use as coloring agent and for a wide variety of disorders. Here, the antiproliferative activity of curcumin and its modulatory effect on gene expression of pancreatic… CONTINUE READING