Upregulation of blood proBDNF and its receptors in major depression.

  title={Upregulation of blood proBDNF and its receptors in major depression.},
  author={Li Zhou and Jing Xiong and Yoon Lim and Ye Ruan and Chaohong Huang and Yuhong Zhu and Jin-hua Zhong and Zhicheng Xiao and Xin-fu Zhou},
  journal={Journal of affective disorders},
  volume={150 3},
BACKGROUND In recent decades, the role of brain-derived neurotrophic factor (BDNF) in depression has received intensive attention. However, the relationship between proBDNF and depression has not been clearly elucidated. METHODS Forty drug-free women patients diagnosed with major depression and 50 healthy female controls were enrolled in our study. Peripheral blood was sampled from all the subjects. With the blood samples, we assessed the relationship between BDNF and major depression from… CONTINUE READING