Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase.

@article{Lecona2008UpregulationOA,
  title={Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase.},
  author={Emilio Lecona and Juan Ignacio Barrasa and Nieves Olmo and Bernab{\'e} Llorente and Javier Turnay and Ma Antonia Lizarbe},
  journal={Molecular and cellular biology},
  year={2008},
  volume={28 15},
  pages={4665-74}
}
Annexin A1 is a member of a phospholipid and calcium binding family of proteins; it is involved in anti-inflammation and in the regulation of differentiation, proliferation, and apoptosis. Here, we show the existence of a functional binding site for the tumor suppressor p53 near the proximal CCAAT box and the fact that the basal expression of annexin A1 in human colon adenocarcinoma cells is driven by p53 at the transcriptional level. Posttranscriptional mechanisms may also play an important… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 4 Excerpts
Highly Influenced

Annexin A1: Uncovering the Many Talents of an Old Protein

International journal of molecular sciences • 2018
View 1 Excerpt

Similar Papers

Loading similar papers…