Upregulation of alpha-synuclein by lipopolysaccharide and interleukin-1 in human macrophages.

Abstract

Alpha-synuclein was originally identified as the presynaptic nerve terminal protein. Recently, we reported that alpha-synuclein is also expressed in cultured human astrocytes and that its levels are increased by stimulation with interleukin-1beta, suggesting that it may be involved in inflammatory processes. We therefore investigated the effect of… (More)

Topics

  • Presentations referencing similar topics