Upregulation of SATB1 promotes tumor growth and metastasis in liver cancer.

@article{Tu2012UpregulationOS,
  title={Upregulation of SATB1 promotes tumor growth and metastasis in liver cancer.},
  author={Wei Hong Tu and Min Luo and Zhijun Wang and Wei Yan and Yujia Xia and Huan Deng and Jiayi He and Ping Han and Dean Tian},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2012},
  volume={32 7},
  pages={1064-78}
}
BACKGROUND Special AT-rich binding protein-1 (SATB1) reprograms chromatin organization and transcription profiles to promote tumour growth and metastasis. AIMS This study aimed to confirm the effects of SATB1 on the growth and metastasis of liver cancer and its specific regulation mechanism. METHODS SATB1 expression was evaluated in human hepatoma tissue, adjacent noncancerous tissue and seven kinds of liver cancer cell lines. Cell cycle, cell proliferation, apoptosis and epithelial… CONTINUE READING