Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells.

@article{Rich2008UpregulationOR,
  title={Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells.},
  author={Jason T. Rich and Ivana Rosov{\'a} and Jan A Nolta and Terence M. Myckatyn and Linda j. Sandell and A Mcalinden},
  journal={Biochemical and biophysical research communications},
  year={2008},
  volume={372 1},
  pages={
          230-5
        }
}
The aim of this study was to create a gene expression profile to better define the phenotype of human adipose-derived stromal cells (HADSCs) during in vitro chondrogenesis, osteogenesis and adipogenesis. A novel aspect of this work was the analysis of the same subset of genes during HADSC differentiation into all three lineages. Chondrogenic induction resulted in increased mRNA expression of Sox transcription factors, COL2A1,COL10A1, Runx2, and Osterix. This is the first report demonstrating… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

miR-483 targets SMAD4 to suppress chondrogenic differentiation of human mesenchymal stem cells.

  • Journal of orthopaedic research : official publication of the Orthopaedic Research Society
  • 2017
VIEW 9 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Cartilage repair: past and future – lessons for regenerative medicine

  • Journal of cellular and molecular medicine
  • 2009
VIEW 17 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED