Upregulation of RAGE and its ligands in proliferative retinal disease.

  title={Upregulation of RAGE and its ligands in proliferative retinal disease.},
  author={Sophia I. Pachydaki and Samir R Tari and Song Eun Lee and Wanchao Ma and Joseph J. Tseng and Alexander A. Sosunov and Guellue Cataldergirmen and Nikolaos Scarmeas and Casper Caspersen and Stanley Chang and William M Schiff and Ann Marie Schmidt and Gaetano Barile},
  journal={Experimental eye research},
  volume={82 5},
We sought to study the presence of the receptor for advanced glycation endproducts (RAGE) and its ligands, advanced glycation endproducts (AGEs), S100/calgranulins and amphoterin (high mobility group box 1 protein; HMGB1), in the vitreous cavity and epiretinal membranes (ERMs) of eyes of patients with proliferative diabetic retinopathy (PDR) and proliferative vitreoretinopathy (PVR). Undiluted vitreous specimens were collected from 30 eyes of 30 patients undergoing pars plana vitrectomy for… CONTINUE READING
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