Upregulation of L-type Ca(v)1 channels in the development of psychological dependence.

@article{Shibasaki2010UpregulationOL,
  title={Upregulation of L-type Ca(v)1 channels in the development of psychological dependence.},
  author={Masahiro Shibasaki and Kazuhiro Kurokawa and Seitaro Ohkuma},
  journal={Synapse},
  year={2010},
  volume={64 6},
  pages={440-4}
}
Although L-type voltage-dependent Ca2+ channels regulate activity-dependent processes including synaptic plasticity and synapse formation, there are few data on the changes of Ca(v)1 channel expression in psychological dependence. This study investigated the role of L-type Ca(v)1 channel expression in the brain of mouse that was psychologically dependent on methamphetamine (2 mg/kg, subcutaneous injection [s.c.]), cocaine (10 mg/kg, s.c.), and morphine (5 mg/kg, s.c.) with the conditioned place… CONTINUE READING