Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases.

@article{Baldwin2006UpregulationOE,
  title={Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases.},
  author={C. Baldwin and Z. W. Chen and A. Bedirian and N. Yokota and S. Nasr and H. Rabb and S. Lemay},
  journal={American journal of physiology. Renal physiology},
  year={2006},
  volume={291 5},
  pages={
          F960-71
        }
}
Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury in both native kidneys and renal allografts. Disruption of the actin cytoskeleton is a key event with multiple repercussions on cell adhesion and function during IRI. However, receptors involved in regulating cytoskeletal repair following injury have not been identified. In an in vivo model of renal IRI, we used multiprobe RNase protection assay to examine the expression of Eph receptor tyrosine kinases, key regulators of… Expand
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