Upregulation of CREM-1 Relates to Retinal Ganglion Cells Apoptosis After Light-Induced Damage In Vivo

@article{Xu2013UpregulationOC,
  title={Upregulation of CREM-1 Relates to Retinal Ganglion Cells Apoptosis After Light-Induced Damage In Vivo},
  author={Yue Xu and Shanshan Yu and Qinmeng Shu and Lu Yang and Cheng Yang and Jiawei Wang and Fan Xu and Min Ji and Xiaoling Liang},
  journal={Journal of Molecular Neuroscience},
  year={2013},
  volume={52},
  pages={331-338}
}
Previous studies have shown activation of cyclic AMP response element-binding protein (CREB) family is involved in the retinal ganglion cells (RGCs) protection. However, the function of cyclic AMP response element modulator-1 (CREM-1), one member of the CREB family, is still with limited acquaintance. To investigate whether CREM-1 is involved in RGCs death, we performed a light-induced retinal damage model in adult rats. Upregulation of CREM-1 was observed in retina after light-induced damage… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

Similar Papers

Loading similar papers…