Upregulation of Bone Morphogenetic Protein 4 is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

Xiaodong Guo, Lu Xiong, Lin Zou, Jingmin Zhao
Published 2011 in Pathology & Oncology Research

Abstract

Bone morphogenetic protein (BMP) 4 plays a crucial role in tumor invasion and metastasis of various human cancers. However, little is known about the correlation of BMP4 expression with clinical aggressiveness and prognosis in hepatocellular carcinoma (HCC). The aim of this study was to investigate the expression of BMP4 in HCC and determine its correlation… (More)

DOI: 10.1007/s12253-011-9488-2

Citations per Year

Citation Velocity: 5

Averaging 5 citations per year over the last 3 years.

Learn more about how we calculate this metric in our FAQ.

Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.

Karen McLean, Yusong Gong, +8 authors Ronald J Buckanovich
The Journal of clinical investigation
2011

Upregulation of Bone Morphogenetic Protein 4 is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

Abstract

Topics

5 Figures and Tables

Statistics

Citation Velocity: 5

Cited By

BMP-4 Genetic Variants and Protein Expression Are Associated with Platinum-Based Chemotherapy Response and Prognosis in NSCLC

BMP4 enhances hepatocellular carcinoma proliferation by promoting cell cycle progression via ID2/CDKN1B signaling.

BMP signaling and its paradoxical effects in tumorigenesis and dissemination

BMP9-Induced Survival Effect in Liver Tumor Cells Requires p38MAPK Activation

Combined aberrant expression of N-Myc downstream-regulated gene 2 and CD24 is associated with disease-free survival and overall survival in patients with hepatocellular carcinoma

Cyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma

Increased level of nucleolin confers to aggressive tumor progression and poor prognosis in patients with hepatocellular carcinoma after hepatectomy

MicroRNA-224 upregulation and AKT activation synergistically predict poor prognosis in patients with hepatocellular carcinoma.

Overexpression of retinoic acid-induced protein 3 predicts poor prognosis for hepatocellular carcinoma.

Atlas of Genetics and Cytogenetics in Oncology and Haematology BMP 4 ( bone morphogenetic protein 4 )

References

Genetic variation in bone morphogenetic protein and colon and rectal cancer.

BMP4 promotes prostate tumor growth in bone through osteogenesis.

Bone morphogenetic protein -4 and -5 in pancreatic cancer--novel bidirectional players.

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

Disclosure of a stem cell phenotype in an oral squamous cell carcinoma cell line induced by BMP-4 via an epithelial-mesenchymal transition.

Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma

Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer.

Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.

mRNA expression of bone morphogenetic proteins and their receptors in human renal cell carcinoma.

Combined lysosomal protein transmembrane 4 beta-35 and argininosuccinate synthetase expression predicts clinical outcome in hepatocellular carcinoma patients

Slides referencing similar topics

Upregulation of Bone Morphogenetic Protein 4 is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

Abstract

Topics

5 Figures and Tables

Statistics

Citation Velocity: 5

Cited By

BMP-4 Genetic Variants and Protein Expression Are Associated with Platinum-Based Chemotherapy Response and Prognosis in NSCLC

BMP4 enhances hepatocellular carcinoma proliferation by promoting cell cycle progression via ID2/CDKN1B signaling.

BMP signaling and its paradoxical effects in tumorigenesis and dissemination

BMP9-Induced Survival Effect in Liver Tumor Cells Requires p38MAPK Activation

Combined aberrant expression of N-Myc downstream-regulated gene 2 and CD24 is associated with disease-free survival and overall survival in patients with hepatocellular carcinoma

Cyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma

Increased level of nucleolin confers to aggressive tumor progression and poor prognosis in patients with hepatocellular carcinoma after hepatectomy

MicroRNA-224 upregulation and AKT activation synergistically predict poor prognosis in patients with hepatocellular carcinoma.

Overexpression of retinoic acid-induced protein 3 predicts poor prognosis for hepatocellular carcinoma.

Atlas of Genetics and Cytogenetics in Oncology and Haematology BMP 4 ( bone morphogenetic protein 4 )

References

Genetic variation in bone morphogenetic protein and colon and rectal cancer.

BMP4 promotes prostate tumor growth in bone through osteogenesis.

Bone morphogenetic protein -4 and -5 in pancreatic cancer--novel bidirectional players.

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

Disclosure of a stem cell phenotype in an oral squamous cell carcinoma cell line induced by BMP-4 via an epithelial-mesenchymal transition.

Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma

Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer.

Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.

mRNA expression of bone morphogenetic proteins and their receptors in human renal cell carcinoma.

Combined lysosomal protein transmembrane 4 beta-35 and argininosuccinate synthetase expression predicts clinical outcome in hepatocellular carcinoma patients

Similar Papers

Slides referencing similar topics