Upregulation of ATF3 inhibits expression of the pro-inflammatory cytokine IL-6 during Neisseria gonorrhoeae infection.

Abstract

Neisseria gonorrhoeae regulates the expression of epithelial cell genes, activates cytoprotective pathways in the infected cell and protects it from apoptosis. Many of these responses are enhanced by the Type IV pilus (Tfp). We tested the hypothesis that N. gonorrhoeae modulates the innate immune response by inducing expression of ATF3, a transcription… (More)

DOI: 10.1111/cmi.12153

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Cited By

TLR4 Mediates Pneumolysin-Induced ATF3 Expression through the JNK/p38 Pathway in Streptococcus pneumoniae-Infected RAW 264.7 Cells

Cuong Thach Nguyen, Eun-Hye Kim, Truc Thanh Luong, Suhkneung Pyo, Dong-Kwon Rhee
Molecules and cells
2015

ATF3 confers resistance to pneumococcal infection through positive regulation of cytokine production.

Cuong Thach Nguyen, Eun-Hye Kim, Truc Thanh Luong, Suhkneung Pyo, Dong-Kwon Rhee
The Journal of infectious diseases
2014

ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration

Jun Zhou, Bruce A Edgar, Michael Boutros
Nature communications
2017

Detection of several serum factors in neonatal gonococcal conjunctivitis and its clinical significance

Huihui Zhu, Bin Lu, Caiping Shi, Huaying Xie, Yanhong Ren, Jia Feng
2017

Attenuation of the Type IV Pilus Retraction Motor Influences Neisseria gonorrhoeae Social and Infection Behavior

Alyson M Hockenberry, Danielle M Hutchens, Al Agellon, Magdalene So
mBio
2016

The prevalence of Chlamydia trachomatis and Mycoplasma genitalium tubal infections and their effects on the expression of IL-6 and leukaemia inhibitory factor in Fallopian tubes with and without an ectopic pregnancy.

Bassem Refaat, Ahmed Mohamed Ashshi, +5 authors Fadi Fayez Kamfar
Innate immunity
2016

Different Mouse Asthma Models Responses and Airway Remodeling in Neurturin Influences Inflammatory

Neurturin influences inflammatory responses and airway remodeling in different mouse asthma models.

Marion Mauffray, Olivia Domingues, François Hentges, Jacques Zimmer, Daniel Hanau, Tatiana Michel
Journal of immunology
2015

References

Sorry, we couldn't extract any references for this paper.

Slides referencing similar topics

Vaccine Development for Neisseria gonorrhoeae
Ann E. Jerse + 1 • Sep 22, 2017
Neisseria meningitidis and N. gonorrhoeae (and M. catarrhalis)
Ellen Jo Baron • Oct 27, 2017
UKZN INSPIRING GREATNESS Tetracycline resistance in Neisseria gonorrhoeae
Santhuri Rambaran + 4 • Oct 19, 2017
Show More