Upregulated expression of Toll-like receptor 4 in peripheral blood of ischaemic stroke patients correlates with cyclooxygenase 2 expression.

@article{Ferronato2011UpregulatedEO,
  title={Upregulated expression of Toll-like receptor 4 in peripheral blood of ischaemic stroke patients correlates with cyclooxygenase 2 expression.},
  author={Silvia Ferronato and Macarena Gomez Lira and Silvia Olivato and Alberto Scuro and Gian Franco Veraldi and Maria Grazia Romanelli and Cristina Patuzzo and Giovanni Malerba and Pier Franco Pignatti and Sara Mazzucco},
  journal={European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery},
  year={2011},
  volume={41 3},
  pages={358-63}
}
OBJECTIVES An inflammatory process following stroke in human brains and systemic inflammatory responses after stroke in humans have been reported by numerous investigators. The aim of the study was to investigate if genes involved in the cyclooxygenase 2 (COX-2) pathway are upregulated at peripheral level in patients after transient ischaemic attack (TIA) and stroke. DESIGN OF STUDY Blood samples were obtained from two groups of patients undergoing carotid endarterectomy. The first group… CONTINUE READING

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