Upregulated and downregulated transcription of myocardial genes after pulmonary artery banding in pigs.

BACKGROUND Acute or chronic pressure overload may occur during or after cardiac surgical procedures. Typical examples are aortic cross-clamping and pulmonary artery banding. It is well known that mechanical stress induces transcription of different myocardial genes. However, these results were mainly obtained from in vitro studies and experiments with… CONTINUE READING