Upper tract urothelial carcinomas: frequency of association with mismatch repair protein loss and lynch syndrome

@article{Harper2017UpperTU,
  title={Upper tract urothelial carcinomas: frequency of association with mismatch repair protein loss and lynch syndrome},
  author={Holly L Harper and Jesse K McKenney and Brandie Heald and Andrew Stephenson and Steven C Campbell and Thomas P. Plesec and Cristina Magi-Galluzzi},
  journal={Modern Pathology},
  year={2017},
  volume={30},
  pages={146-156}
}
Increased risk for upper tract urothelial carcinoma is described in patients with Lynch syndrome, caused by germline mutations in mismatch repair genes. We aimed to identify the frequency of mismatch repair protein loss in upper tract urothelial carcinoma and its potential for identifying an association with Lynch syndrome. We queried our database to… CONTINUE READING