Upper airway pressure-flow relationships in obstructive sleep apnea.

@article{Smith1988UpperAP,
  title={Upper airway pressure-flow relationships in obstructive sleep apnea.},
  author={Philip L. Smith and Robert A. Wise and Avram R. Gold and Alan R. Schwartz and Solbert Permutt},
  journal={Journal of applied physiology},
  year={1988},
  volume={64 2},
  pages={789-95}
}
We examined the pressure-flow relationships in patients with obstructive sleep apnea utilizing the concepts of a Starling resistor. In six patients with obstructive sleep apnea, we applied incremental levels of positive pressure through a nasal mask during non-rapid-eye-movement sleep. A positive critical opening pressure (Pcrit) of 3.3 +/- 3.3 (SD) cmH2O was demonstrated. As nasal pressure was raised above Pcrit, inspiratory airflow increased in proportion to the level of positive pressure… CONTINUE READING

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