Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea.

@article{McGinley2008UpperAN,
  title={Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea.},
  author={Brian M. McGinley and Alan R. Schwartz and Hartmut Schneider and Jason P. Kirkness and Philip L. Smith and Susheel P. Patil},
  journal={Journal of applied physiology},
  year={2008},
  volume={105 1},
  pages={197-205}
}
Obstructive sleep apnea is the result of repeated episodes of upper airway obstruction during sleep. Recent evidence indicates that alterations in upper airway anatomy and disturbances in neuromuscular control both play a role in the pathogenesis of obstructive sleep apnea. We hypothesized that subjects without sleep apnea are more capable of mounting vigorous neuromuscular responses to upper airway obstruction than subjects with sleep apnea. To address this hypothesis we lowered nasal pressure… CONTINUE READING

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