Upper Limb Recovery After Stroke Is Associated With Ipsilesional Primary Motor Cortical Activity: A Meta-Analysis

@article{Favre2014UpperLR,
  title={Upper Limb Recovery After Stroke Is Associated With Ipsilesional Primary Motor Cortical Activity: A Meta-Analysis},
  author={Isabelle Favre and Thomas A. Zeffiro and Olivier Detante and Alexandre Krainik and Marc Hommel and Assia Jaillard},
  journal={Stroke},
  year={2014},
  volume={45},
  pages={1077–1083}
}
Background and Purpose— Although neuroimaging studies have revealed specific patterns of reorganization in the sensorimotor control network after stroke, their role in recovery remains unsettled. To review the existing evidence systematically, we performed activation likelihood estimation meta-analysis of functional neuroimaging studies investigating upper limb movement-related brain activity after stroke. Methods— Twenty-four studies using sensorimotor tasks in standardized coordinates were… 

Cortical reorganization after motor stroke: A pilot study on differences between the upper and lower limbs

TLDR
The level of neural activity underlying movements of the affected right hand and foot positively correlated with residual motor impairment, in both ipsilesional and contralesional premotor as well as left primary motor regions is found.

Bilateral versus ipsilesional cortico-subcortical activity patterns in stroke show hemispheric dependence

TLDR
The observed hemispheric-dependent activation/deactivation shifts are novel and these pathophysiological observations suggest short-term neuroplasticity that may be useful for hemisphere-tailored neurorehabilitation.

Bilateral versus ipsilesional cortico-subcortical activity patterns in stroke show hemispheric dependence.

TLDR
The observed hemispheric-dependent activation/deactivation shifts is novel and these pathophysiological observations suggest short-term neuroplasticity that may be useful for hemisphere-tailored neurorehabilitation.

Time course of sensorimotor cortex reorganization during upper extremity task accompanying motor recovery early after stroke: An fNIRS study.

TLDR
Cortical reorganization monitoring using fNIRS during the first weeks after stroke may be applied for assessing progressive brain plasticity in addition to clinical measures of performance.

Increased Sensorimotor Cortex Activation With Decreased Motor Performance During Functional Upper Extremity Tasks Poststroke

TLDR
Larger sensorimotor activations in the ipsilesional hemisphere were found for the stroke compared with healthy group for reaching and gripping conditions despite poorer performance, which may indicate an increased sense of effort, decreased efficiency, or increased difficulty after stroke.

Ipsilateral primary motor cortex and behavioral compensation after stroke: a case series study

TLDR
The preliminary results suggest that iM1 may play a role in compensating for brain damage rather than directly gaining control of the paretic arm, and recommend caution in interpreting these results until more work is completed.

Brain Functional Topology Alteration in Right Lateral Occipital Cortex Is Associated With Upper Extremity Motor Recovery

TLDR
It is suggested that brain functional topologies alterations in R LOC are promising as prognostic biomarkers for right-sided subacute stroke and this cortical area might be a potential target to be further validated for non-invasive brain stimulation treatment to improve poststroke upper extremity recovery.

Intervention-Induced Changes in Cortical Connectivity and Activity in Severe Chronic Hemiparetic Stroke

TLDR
The results suggest that changes in cortico-cortico interactions may lead to corresponding changes in focal cortical activity at movement execution and connectivity during movement preparation.
...

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