Upmodulation of multinucleated cell formation in long-term human bone marrow cultures by leukaemia inhibitory factor (LIF).

@article{Heymann1997UpmodulationOM,
  title={Upmodulation of multinucleated cell formation in long-term human bone marrow cultures by leukaemia inhibitory factor (LIF).},
  author={Dominique Heymann and F. Gouin and J{\'e}r{\^o}me Guicheux and J C Munevar and Anne Godard and Guy Daculsi},
  journal={Cytokine},
  year={1997},
  volume={9 1},
  pages={46-52}
}
Inflammatory processes are mediated by many cellular events involving different cell types (leukocytes, monocytes, stromal cells, etc.). Numerous soluble mediators regulate these reactions, including leukaemia inhibitory factor (LIF), a cytokine which may play an important role in inducing acute-phase protein synthesis by hepatocytes during inflammation. This study was designed to determine the effects of LIF on the human monocyte/macrophage lineage and provide a better definition of its… CONTINUE READING

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