Upk3b Is Dispensable for Development and Integrity of Urothelium and Mesothelium

@inproceedings{Rudat2014Upk3bID,
  title={Upk3b Is Dispensable for Development and Integrity of Urothelium and Mesothelium},
  author={Carsten Rudat and Thomas Grieskamp and Christian R{\"o}hr and Rannar Airik and Christoph Wrede and Jan Hegermann and Bernhard G Herrmann and Karin Schuster-Gossler and Andreas Kispert},
  booktitle={PloS one},
  year={2014}
}
The mesothelium, the lining of the coelomic cavities, and the urothelium, the inner lining of the urinary drainage system, are highly specialized epithelia that protect the underlying tissues from mechanical stress and seal them from the overlying fluid space. The development of these epithelia from simple precursors and the molecular characteristics of the mature tissues are poorly analyzed. Here, we show that uroplakin 3B (Upk3b), which encodes an integral membrane protein of the tetraspanin… CONTINUE READING

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