Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.

@article{Vreven2015UpdatesTT,
  title={Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.},
  author={T. Vreven and I. Moal and A. Vangone and B. Pierce and P. Kastritis and Mieczyslaw Torchala and Raphael A. G. Chaleil and B. Jim{\'e}nez-Garc{\'i}a and P. Bates and J. Fern{\'a}ndez-Recio and A. Bonvin and Z. Weng},
  journal={Journal of molecular biology},
  year={2015},
  volume={427 19},
  pages={
          3031-41
        }
}
We present an updated and integrated version of our widely used protein-protein docking and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality structures of protein-protein complexes along with the unbound structures of their components. Fifty-five new complexes were added to the docking benchmark, 35 of which have experimentally measured binding affinities. These updated docking and affinity benchmarks now contain 230 and 179 entries, respectively. In particular… Expand
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