Updated report on tools to measure outcomes of clinical trials in fragile X syndrome

  title={Updated report on tools to measure outcomes of clinical trials in fragile X syndrome},
  author={Dejan B. Budimirovic and Elizabeth M. Berry-Kravis and Craig A. Erickson and Scott S Hall and David Hessl and Allan L. Reiss and Margaret K. King and Leonard J Abbeduto and Walter E. Kaufmann},
  booktitle={Journal of Neurodevelopmental Disorders},
Fragile X syndrome (FXS) has been the neurodevelopmental disorder with the most active translation of preclinical breakthroughs into clinical trials. This process has led to a critical assessment of outcome measures, which resulted in a comprehensive review published in 2013. Nevertheless, the disappointing outcome of several recent phase III drug trials in FXS, and parallel efforts at evaluating behavioral endpoints for trials in autism spectrum disorder (ASD), has emphasized the need for re… CONTINUE READING
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