Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transporters.

@article{Moccia2012UpdateOV,
  title={Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transporters.},
  author={Francesco Moccia and Roberto Berra-Romani and Franco Tanzi},
  journal={World journal of biological chemistry},
  year={2012},
  volume={3 7},
  pages={
          127-58
        }
}
A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and forms a multifunctional transducing organ that mediates a plethora of cardiovascular processes. The activation of ECs from as state of quiescence is, therefore, regarded among the early events leading to the onset and progression of potentially lethal diseases, such as hypertension, myocardial infarction, brain stroke, and tumor. Intracellular Ca(2+) signals have long been know to play a central role in the complex… CONTINUE READING

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