Update on typical and atypical antipsychotic drugs.

@article{Meltzer2013UpdateOT,
  title={Update on typical and atypical antipsychotic drugs.},
  author={Herbert Y Meltzer},
  journal={Annual review of medicine},
  year={2013},
  volume={64},
  pages={
          393-406
        }
}
Antipsychotic drugs (APDs) are best classified as typical or atypical. The distinction is based solely on their ability to cause extrapyramidal side effects (EPS), including tardive dyskinesia (TD). The two classes differ in mechanism of action, with atypical APDs providing important modulation of serotonergic neurotransmission. TD increases the death rate and can be minimized by limiting use of typical APDs. Clozapine is unique among the atypical APDs in its efficacy for ameliorating psychosis… CONTINUE READING

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Clozapine: a consideration of its benefits and risks

  • HY Meltzer
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