Update on the mechanisms and roles of high-frequency oscillations in seizures and epileptic disorders.

@article{Jiruska2017UpdateOT,
  title={Update on the mechanisms and roles of high-frequency oscillations in seizures and epileptic disorders.},
  author={Premysl Jiruska and Catalina Alvarado-Rojas and Catherine A. Schevon and Richard Staba and William C. Stacey and Fabrice Wendling and Massimo Avoli},
  journal={Epilepsia},
  year={2017},
  volume={58 8},
  pages={
          1330-1339
        }
}
High-frequency oscillations (HFOs) are a type of brain activity that is recorded from brain regions capable of generating seizures. Because of the close association of HFOs with epileptogenic tissue and ictogenesis, understanding their cellular and network mechanisms could provide valuable information about the organization of epileptogenic networks and how seizures emerge from the abnormal activity of these networks. In this review, we summarize the most recent advances in the field of HFOs… CONTINUE READING

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HFOs have also been reported to occur in other epileptic disorders and models such as neocortical epilepsy , genetically determined epilepsies , and infantile spasms , which further support the significance of HFOs in the pathophysiology of epilepsy .
HFOs have also been reported to occur in other epileptic disorders and models such as neocortical epilepsy , genetically determined epilepsies , and infantile spasms , which further support the significance of HFOs in the pathophysiology of epilepsy .
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