Update on the efficacy of statin treatment in acute coronary syndromes

  title={Update on the efficacy of statin treatment in acute coronary syndromes},
  author={G. M. Rosa and F. Carbone and A. Parodi and E. A. Massimelli and C. Brunelli and F. Mach and N. Vuilleumier and F. Montecucco},
  journal={European Journal of Clinical Investigation},
  pages={501 - 515}
  • G. M. Rosa, F. Carbone, +5 authors F. Montecucco
  • Published 2014
  • Medicine
  • European Journal of Clinical Investigation
  • The natural history of atherosclerosis might involve coronary plaque rupture/erosion, thrombus formation and vessel lumen occlusion, clinically recognized as acute coronary syndrome (ACS). International guidelines strongly recommend early statin administration in patients admitted for ACS. In addition to lowering circulating levels of low‐density lipoprotein cholesterol (LDL‐c), statin treatment was shown to promote plaque stabilization or regression in several ways, including reduction in… CONTINUE READING
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