Update on the differential diagnosis, surveillance and management of hereditary non-polyposis colorectal cancer.

@article{Lynch1995UpdateOT,
  title={Update on the differential diagnosis, surveillance and management of hereditary non-polyposis colorectal cancer.},
  author={Henry T. Lynch and Thomas C. Smyrk and Jane F. Lynch and Robert Joseph Fitzgibbons and Stephen J. Lanspa and Thomas McGinn},
  journal={European journal of cancer},
  year={1995},
  volume={31A 7-8},
  pages={1039-46}
}
Hereditary non-polyposis colorectal cancer (HNPCC) is the most common hereditary form of colorectal cancer (CRC), accounting for approximately 10% of the total CRC burden. HNPCC lacks premonitory physical stigmata, thereby making the family history crucial for diagnosis. Advances in molecular genetics during the past 2 years have led to the cloning of four… CONTINUE READING