Update on the Use of Biologic Therapy in Ulcerative Colitis.

  title={Update on the Use of Biologic Therapy in Ulcerative Colitis.},
  author={Aakash Aggarwal and Timothy P. Sabol and Haleh Vaziri},
  journal={Current treatment options in gastroenterology},
  volume={15 1},
OPINION STATEMENT Ulcerative colitis (UC) is a major form of inflammatory bowel disease and is characterized by chronic inflammation of the colon and rectum and by alternating periods of flares and remissions. Symptoms may include rectal bleeding, abdominal pain, and diarrhea. The pathogenesis of UC is complex and involves a combination of immune dysregulation, genetics, environmental factors, and microbiota. The goal of medical treatment is to induce and maintain remission. Traditionally, the… CONTINUE READING
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