Update on strategies to increase HDL quantity and function

  title={Update on strategies to increase HDL quantity and function},
  author={Danielle Duffy and Daniel J. Rader},
  journal={Nature Reviews Cardiology},
Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol transport, and potentially through anti-inflammatory, antioxidative, antithrombotic and nitric oxide effects. The multiple mechanisms of action, as well as a limited ability to measure these properties, make HDL a complex therapeutic target, albeit one with immense potential for the treatment of patients with… CONTINUE READING

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