Update on pruritic mechanisms of hypertrophic scars in postburn patients: the potential role of opioids and their receptors.

@article{Cheng2011UpdateOP,
  title={Update on pruritic mechanisms of hypertrophic scars in postburn patients: the potential role of opioids and their receptors.},
  author={Biao Cheng and Hongwei Liu and Xiaobing Fu},
  journal={Journal of burn care & research : official publication of the American Burn Association},
  year={2011},
  volume={32 4},
  pages={e118-25}
}
Although itching (or pruritus) in a scar is a very common and distressing symptom and is increasingly being recognized as a significant obstacle in burn rehabilitation, the exact mechanisms underlying this symptom have not been elucidated; hence, a reliable therapy has not been established. Recent findings have suggested that itching caused by inflammatory dermatosis can be reduced by antihistamines, but histamine antagonists cannot block all types of pruritus (eg, neuropathic itch). This… CONTINUE READING
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